-80℃储存，低温运输。
包装内容：
产品编号 | 产品名称 | 包装 |
N1117 | AsdCas12a mRNA (1mg/ml) | 100/1000μg |
产品简介：
名称/别名：AsdCas12a (Acidaminococcus sp. Cas12a nuclease-deactivated)
CRISPR类型：Type V
活性：转录抑制（CRISPRi）和激活（CRISPRa）
特性：识别TTN PAM位点，融合KRAB或VPR域进行转录调控
应用：人类细胞中的基因表达调控和转录控制
CDS (4974nt):
atgacacagttcgagggctttaccaacctgtatcaggtgagcaagacactgcggtttgagctgatcccacagggcaagaccctgaagcacatccaggagcagggcttcatcgaggaggacaaggcccgcaatgatcactacaagga
gctgaagcccatcatcgatcggatctacaagacctatgccgaccagtgcctgcagctggtgcagctggattgggagaacctgagcgccgccatcgactcctatagaaaggagaaaaccgaggagacaaggaacgccctgatcgag
gagcaggccacatatcgcaatgccatccacgactacttcatcggccggacagacaacctgaccgatgccatcaataagagacacgccgagatctacaagggcctgttcaaggccgagctgtttaatggcaaggtgctgaagcagctg
ggcaccgtgaccacaaccgagcacgagaacgccctgctgcggagcttcgacaagtttacaacctacttctccggcttttatgagaacaggaagaacgtgttcagcgccgaggatatcagcacagccatcccacaccgcatcgtgcag
gacaacttccccaagtttaaggagaattgtcacatcttcacacgcctgatcaccgccgtgcccagcctgcgggagcactttgagaacgtgaagaaggccatcggcatcttcgtgagcacctccatcgaggaggtgttttccttcccttttta
taaccagctgctgacacagacccagatcgacctgtataaccagctgctgggaggaatctctcgggaggcaggcaccgagaagatcaagggcctgaacgaggtgctgaatctggccatccagaagaatgatgagacagcccacatc
atcgcctccctgccac………….
参考文献
Escobar, M. et al. Quantification of Genome Editing and Transcriptional Control Capabilities Reveals Hierarchies among Diverse CRISPR/Cas Systems in Human Cells. ACS Synth. Biol. 2022, 11, 3239–3250.
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