-80℃储存，低温运输。
包装内容：
产品编号 | 产品名称 | 包装 |
N1137 | PxCas12a mRNA (1mg/ml) | 100/1000μg |
产品简介：
名称/别名：PxCas12a（Parvibaculum xylanivorans Cas12a）
CRISPR类型：Type V-A
肽链长度：约1200-1300个氨基酸（aa）
介导哺乳动物细胞基因组编辑
识别5'-TTTN PAM
依赖天然crRNA支架（scaffold 1）
编辑效率可通过优化crRNA支架（如4n96）提升
CDS (4593nt):
atgcccaagaagaagaggaaggttcccgggatgatcatcggccgcgacttcaacatgtactaccagaacctgaccaagatgtaccccatcagcaagaccctgcgcaacgagctgatccccgtgggcaagaccctggagaacatcc
gcaagaacggcatcctggaggccgacatccagcgcaaggccgactacgagcacgtgaagaagctgatggacaactaccacaagcagctgatcaacgaggccctgcagggcgtgcacctgagcgacctgagcgacgcctacga
cctgtacttcaacctgagcaaggagaagaacagcgtggacgccttcagcaagtgccaggacaagctgcgcaaggagatcgtgagcttcctgaagaaccacgagaacttccccaagatcggcaacaaggagatcatcaagctgatcc
agagcctgaacgacaacgacgccgacaacaacgccctggacagcttcagcaacttctacacctacttcagcagctacaacgaggtgcgcaagaacctgtacagcgacgaggagaagagcagcaccgtggcctaccgcctgatca
acgagaacctgcccaagagcctggacaacatcaaggcctacgccatcgccaagaaggccggcgtgcgcgccgagggcctgagcgaggaggagcaggactgcctgttcatcatcgagaccttcgagcgcaccctgacccaggac
ggcatcgacaactacaacgccgacatcggcaagctgaacaccgccatcaacctgtacaaccagcagaacaagaagcaggagggcttccgcaaggtgccccagatgaagtgcctgtacaagcagatcctgagcgaccgcgagga
ggccttcatcgacgagttcagcgacgacgaggacctgatcaccaacatcgag………….
参考文献
Teng, F. et al. Enhanced mammalian genome editing by new Cas12a orthologs with optimized crRNA scaffolds. Nat. Commun. 10, 1234 (2019).
可选项：
