-80℃储存，低温运输。
包装内容：
产品编号 | 产品名称 | 包装 |
N1177 | bzCas13b mRNA (1mg/ml) | 100/1000μg |
产品简介：
名称/别名：bzCas13b（Bergeyella zoohelcum Cas13b）
CRISPR类型：VI-B1
肽链长度：约 1100 aa（文献未明确，依据系统特征推断）
活性：RNA 引导的 RNase，具有特异性切割及非特异性（collateral）RNA 降解活性
依赖双面原间隔序列（5' PFS: D/A/U/G；3' PFS: NAN/NNA）
受 Csx27 抑制，受 Csx28 增强
具有预 crRNA 自主加工能力
CDS (3675nt):
atggaaaacaaaacatctttggggaataatatttattacaacccttttaaaccacaagataaatcgtattttgcgggttatttcaatgcagcaatggaaaatacagatagtgtatttagagaattgggaaaaagattaaaaggtaaagagtacac
ttcggagaatttttttgatgctatctttaaggaaaatatttcattagtggaatacgaaaggtatgtgaaattgctttctgattatttccctatggctcgtcttttggataaaaaagaagttcctataaaagaacgaaaagaaaattttaaaaagaatttt
aaaggcattataaaagccgtaagagatttaagaaacttttatacgcataaggaacacggagaggtagaaattacagatgaaatatttggcgtattggatgagatgctgaaaagcacggttttaacggtaaaaaagaaaaaagtaaaaacc
gataaaacaaaagaaatcctgaaaaaaagcatagaaaaacaattggatattttatgccaaaagaaattagaatatctaagagacacagcaagaaaaatagaggagaagcgtagaaatcaaagagaaagaggagagaaagaattggta
gctccattcaaatacagtgataaaagggatgatttaatagcagcgatttataatgatgcttttgatgtttatatcgataagaaaaaagatagcctaaaagaatccagcaaagcaaagtacaataccaaaagtgatcctcagcaagaagaagg
cgatttgaaaattccaatttcgaaaaacggagtagtcttcctgctttctttgtttctcaccaaacaagaaatacacgcattcaaatctaaaatagcagggtttaaggctacggttatcgatgaagcaacggtatctgaagcaacggtgagccat
ggaaaaaacagcatttgttttatggctacgcacgaaattttctcgcatttggcttacaaaaaattgaaacgaaaagtgagaacggctgaaatcaactatggtgaggcagaaaa………….
参考文献
Smargon, A. A. et al. Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28. Mol. Cell 65, 618–630 (2017).
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