-80℃储存，低温运输。
包装内容：
产品编号 | 产品名称 | 包装 |
N1272 | CpAgo mRNA (1mg/ml) | 100/1000μg |
产品简介：
全称：Clostridium perfringensArgonaute (产气荚膜梭菌Argonaute蛋白)
类型：原核Argonaute蛋白 (pAgo)
来源：Clostridium perfringens(产气荚膜梭菌)，一种中温细菌。
核心特征：一种在37°C下具有高效催化活性的核酸酶，兼具不依赖引导链和DNA引导的双重催化功能。
氨基酸序列（751aa）
MVGGYKVSNLTVEAFEGIGSVNPMLFYQYKVTGKGKYDNVYKIIKSARYKMHSKNRFKPVFIKDDKLYTLEKLPDIEDLDFANINFVKSEVLSIEDN
MSIYGEVVEYYINLKLKKVKVLGKYPKYRINYSKEILSNTLLTRELKDEFKKSNKGFNLKRKFRISPVVNKMGKVILYLSCSADFSTNKNIYEMLKE
GLEVEGLAVKSEWSNISGNLVIESVLETKISEPTSLGQSLIDYYKNNNQGYRVKDFTDEDLNANIVNVRGNKKIYMYIPHALKPIITREYLAKNDPEFS
KEIEQLIKMNMNYRYETLKSFVNDIGVIEELNNLSFKNKYYEDVKLLGYSSGKIDEPVLMGAKGIIKNKMQIFSNGFYKLPEGKVRFGVLYPKEFDG
VSRKAIRAIYDFSKEGKYHGESNKYIAEHLINVEFNPKECIFEGYELGDITEYKKAALKLNNYNNVDFVIAIVPNMSDEEIENSYNPFKKIWAELNLPS
QMISVKTAEIFANSRDNTALYYLHNIVLGILGKIGGIPWVVKDMKGDVDCFVGLDVGTREKGIHYPACSVVFDKYGKLINYYKPNIPQNGEKINTEIL
QEIFDKVLISYEEENGAYPKNIVIHRDGFSREDLDWYENYFGKKNIKFNIIEVKKSTPLKIASINEGNITNPEKGSYILRGNKAYMVTTDIKENLGSPKP
LKIEKSYGDIDMLTALSQIYALTQIHVGATKSLRLPITTGYADKICKAIEFIPQGRVDNRLFFL
参考文献
Liu, Y. et al. The PAZ pocket and dimerization drive CpAgo’s guide-independent and DNA-guided dual catalysis. Nat. Commun. 16, 6599 (2025).
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